Jeremiah Chamberlain (1740-1829) was the eldest son of Ninian Chamberlain, Sr. (1719-1804) and Jennet Unknown (1720-1784), of Jefferson Co., TN, as family wills and other official documents unmistakably prove. He was an accomplished surveyor. He is said to have come to America from Ireland with his parents and siblings at the age of 16 (c1756). Jeremiah married Margaret Carmichael in 1787, and was the father of nine children, among them Ninian Chamberlain (1792-1877) of Corryton, Knox Co. (where the Chamberlain-Little Family Cemetery came to be located). The couple settled in what was to become Grainger Co. Originally buried in the Chamberlain family cemetery in May Spring, Grainger Co., TN, Jeremiah's body was among those removed to Martha Sunderland Cemetery, Hamblen Co., in the early 1940s to make way for Cherokee Lake. Although his headstone indicates that he died in 1824, his will and probate documents clearly show that he lived until 1829. (He wrote his will on 27 Apr. 1829.) Jeremiah Chamberlain fought in the Revolutionary War as a soldier for NC, reportedly serving as a private at the Battle of Kings Mtn. and afterwards accompanying Col. John Sevier on expeditions against the Chickamauga Tories. In 1796, he was named a member of the first grand jury of the newly formed county of Grainger.
Besides their son Ninian (mentioned above), Jeremiah and Margaret's children included: Mary (Polly), 1788-1872; Jennet, 1790-1870; Daniel C., 1794-1866; Thompson, 1796-1885; Margaret Jane (Peggy), 1799-1877; Elizabeth (Betsy), 1803-1850; Andrew, 1806-1833; and James (1809-1889). Several of them migrated to MO and, in some cases, eventually moved on to TX.