Daughter of Wm. Saunders Calloway and Sarah Ann Hurst. Wife of Wm. H. Chamberlain, of Knox Co., TN, whom she married in 1851 when she was only 14 years old. Wm. and Mary Ellen had eight children: Mary Emeline; Margaret Ann; Florence Adelia; Thos. Ninian; Albert B.; John James; Belle G.; and Daniel H.