Third daughter of Jeremiah Chamberlain (1740-1829) and Margaret Carmichael (1765-1821), of Grainger Co., TN. Wife of Isaac Jones Watkins (1788-1840), of Jefferson Co., TN. Margaret and Isaac Watkins were married in Grainger Co. in Aug. 1821 by the noted pioneer Baptist preacher, Isaac Barton. They had eight children: John M.; Margaret Reese; Wm. Wirt; Thompsey; Abram; Thos. G.; James Osborne; and Lawson Clark. Husband Isaac died in 1840. In 1855, Margaret moved to TX with her youngest son, Lawson. She is buried on private land in Karnes Co., TX.
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